Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.59 |
| ▸ | ICMT | O60725 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10989612 | 0.91 | MTNR1A (0.60) | MTNR1AMTNR1BICMTMEN1KMT2A | |
| SCHEMBL11114174 | 0.89 | MTNR1A (0.66) | MTNR1AMTNR1BICMTMEN1KMT2A | |
| SCHEMBL12520413 | 0.84 | MTNR1B (0.60) | MTNR1AMTNR1BICMTMEN1KMT2A | |
| SCHEMBL11115757 | 0.84 | MAPT (0.61) | MTNR1AMTNR1BICMTMEN1KMT2A | |
| SCHEMBL11112342 | 0.84 | SMN1; SMN2 (0.47) | MTNR1AMTNR1BMAPTNPSR1GRM4 | |
| SCHEMBL11168082 | 0.84 | MAPT (0.44) | MTNR1AMTNR1BKMT2AMAPTPOLB | |
| SCHEMBL11116182 | 0.83 | ALDH1A1 (0.57) | MTNR1AMTNR1BMAPTMAPK1POLB | |
| SCHEMBL11114326 | 0.83 | EGFR (0.57) | MTNR1AMTNR1BICMTMEN1KMT2A | |
| SCHEMBL10126711 | 0.83 | MTNR1A (0.63) | MTNR1AMTNR1BICMTMEN1KMT2A | |
| SCHEMBL8557540 | 0.83 | MTNR1A (0.63) | MTNR1AMTNR1BICMTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| EP-0058868-A1 | Derivatives of tetrahydropyrimidinon, process for their preparation and herbicides containing those derivatives as active products | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1982-09-01 | — | — | EP | disclosed |