Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2201433 | 0.85 | ALDH1A1 (0.46) | PDE5APTGS1PTGS2HPGDLMNA | |
| SCHEMBL12125057 | 0.78 | ALDH1A1 (0.48) | PTPRCCTSGKLK7KLK14KLK5 | |
| SCHEMBL29982807 | 0.76 | L3MBTL1 (0.50) | PDE5APTPRCKMT2ANPC1GRM5 | |
| SCHEMBL8621133 | 0.75 | PTGS2 (0.47) | PTPRCPTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL28193216 | 0.72 | TRPA1 (0.46) | PDE5AKMT2AGRM5HPGDALDH1A1 | |
| SCHEMBL11284232 | 0.72 | DRD1 (0.41) | PTPRCCTSGKLK7KLK14KLK5 | |
| SCHEMBL5700053 | 0.72 | PTGS2 (0.59) | PTPRCPTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL28185277 | 0.71 | PDE5A (0.53) | PDE5APTPRCNPC1GRM5HPGD | |
| SCHEMBL16113470 | 0.71 | PTGS2 (0.48) | PTPRCPTGS1PTGS2KMT2AMEN1 | |
| SCHEMBL27518574 | 0.71 | CA1 (0.50) | PTPRCKMT2AMEN1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103660-A1 | Pyridine-1-oxides, herbicidal compositions thereof and herbicidal methods for applying the compounds | UNIROYAL, INC. (US) | 1984-03-28 | — | — | EP | disclosed |