Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084374 | 0.92 | PTGS1 (0.35) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11084406 | 0.92 | PTGS1 (0.35) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11073575 | 0.89 | ALDH1A1 (0.36) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11073574 | 0.89 | ALDH1A1 (0.36) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11082041 | 0.88 | PTGS1 (0.36) | PTGS1ALDH1A1CYP3A4L3MBTL1CTDSP1 | |
| SCHEMBL11082044 | 0.88 | PTGS1 (0.36) | PTGS1ALDH1A1CYP3A4L3MBTL1CTDSP1 | |
| SCHEMBL11080922 | 0.88 | CTSS (0.43) | PTGS1 | |
| SCHEMBL11098887 | 0.87 | ALDH1A1 (0.35) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11080150 | 0.83 | ELANE (0.30) | PTGS1PLCG1ELANE | |
| SCHEMBL11080145 | 0.83 | ELANE (0.30) | PTGS1PLCG1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0040494-B1 | CARBAPENAMS AND CARBAPEN-2-EMS AND PROCESS THEREFOR | PFIZER INC. (US) | 1984-02-15 | — | — | EP | disclosed |
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | disclosed |