Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 7/20 | 0.40 |
| ▸ | HTR2C | P28335 | 7/20 | 0.40 |
| ▸ | HRH1 | P35367 | 5/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114768 | 0.93 | HTR2B (0.43) | HTR2BHTR2AHTR2CHRH1ADRA2A | |
| SCHEMBL11117014 | 0.88 | TBXAS1 (0.38) | HTR2BHTR2AHTR2CHRH1ADRA2A | |
| SCHEMBL11113353 | 0.87 | HRH1 (0.41) | HTR2BHTR2AHTR2CHRH1ADRA2A | |
| SCHEMBL11117688 | 0.86 | HTR2B (0.44) | HTR2BHTR2AHTR2CHRH1ADRA2A | |
| SCHEMBL11116048 | 0.85 | TBXAS1 (0.41) | HTR2AHTR2CHRH1TBXAS1GAA | |
| SCHEMBL11114001 | 0.84 | MEN1 (0.40) | HTR2BHTR2AHTR2CHRH1DRD2 | |
| SCHEMBL10911835 | 0.81 | TBXAS1 (0.49) | HTR2CTBXAS1GAAKDM4EALDH1A1 | |
| SCHEMBL11155482 | 0.80 | HTR2A (0.40) | HTR2AHTR2CHRH1TBXAS1KMT2A | |
| SCHEMBL11115157 | 0.79 | HTR2B (0.43) | HTR2BHTR2AHTR2CHRH1ADRA2A | |
| SCHEMBL11115014 | 0.78 | TBXAS1 (0.40) | HTR2AHTR2CHRH1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038564-B1 | DIBENZ (B,E) OXEPIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1984-09-12 | — | — | EP | disclosed |
| US-4396550-A | ANTICHOLINERGIC, ANTIHISTIMINIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-08-02 | — | — | US | disclosed |