Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113353 | 0.93 | HRH1 (0.41) | HTR2AHRH1HTR2CRCE1TBXAS1 | |
| SCHEMBL11111420 | 0.89 | ALOX15 (0.40) | HTR2AHRH1HTR2CTBXAS1TBXA2R | |
| SCHEMBL11115157 | 0.87 | HTR2B (0.43) | HTR2AHRH1HTR2CTBXAS1SLC6A3 | |
| SCHEMBL11114768 | 0.87 | HTR2B (0.43) | HTR2AHRH1HTR2CTBXAS1TBXA2R | |
| SCHEMBL11115014 | 0.86 | TBXAS1 (0.40) | HTR2AHRH1HTR2CTBXAS1SLC6A3 | |
| SCHEMBL11114115 | 0.84 | TBXAS1 (0.39) | HTR2AHRH1HTR2CRCE1TBXAS1 | |
| SCHEMBL11113110 | 0.80 | HTR2B (0.44) | HTR2AHRH1HTR2CTBXAS1TBXA2R | |
| SCHEMBL11117688 | 0.80 | HTR2B (0.44) | HTR2AHRH1HTR2CTBXAS1 | |
| SCHEMBL11116048 | 0.79 | TBXAS1 (0.41) | HTR2AHRH1HTR2CTBXAS1TBXA2R | |
| SCHEMBL11117514 | 0.78 | TBXAS1 (0.38) | TBXAS1TBXA2RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4396550-A | ANTICHOLINERGIC, ANTIHISTIMINIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-08-02 | — | — | US | disclosed |
| EP-0038564-A1 | Dibenz (b,e) oxepin derivatives and pharmaceutical compositions comprising them | KYOWA HAKKO KOGYO CO., LTD (JP) | 1981-10-28 | — | — | EP | disclosed |