Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31161637 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP1A2HPGDHTTMEN1 | |
| SCHEMBL2336306 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP1A2HPGDHTTMEN1 | |
| SCHEMBL8825646 | 0.81 | MEN1 (0.43) | ALDH1A1CYP1A2CYP2C9HPGDHTT | |
| SCHEMBL11111254 | 0.78 | LMNA (0.55) | ALDH1A1HTTMEN1KMT2AL3MBTL1 | |
| SCHEMBL23073990 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HPGDHTTMEN1THRB | |
| SCHEMBL590168 | 0.76 | HPGD (0.46) | ALDH1A1HPGDHTTMEN1THRB | |
| SCHEMBL29536923 | 0.76 | HPGD (0.46) | ALDH1A1HPGDHTTMEN1THRB | |
| SCHEMBL14810207 | 0.76 | HDAC8 (0.40) | ALDH1A1HPGDHTTMEN1THRB | |
| SCHEMBL11116090 | 0.76 | ALDH1A1 (0.39) | ALDH1A1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL837451 | 0.76 | ALDH1A1 (0.56) | ALDH1A1HTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038071-B1 | NEW UNLABELLED AND RADIOACTIVE LABELLED DERIVATIVES OF BUTYLAMINO PROPIOPHENONE, THEIR PREPARATION, IMMUNOGENS OBTAINED FROM THE UNLABELLED DERIVATIVES AND A PROCESS FOR IMMUNOGEN PREPARATION, ANTISERA RAISED USING THE IMMUNOGENS AND A METHOD FOR RAISING ANTISERA, A RADIOIMMUNOASSAY METHOD AND A TEST KIT FOR USE IN THE ASSAY METHOD | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-11-14 | — | — | EP | disclosed |