Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113691 | 0.77 | LOXL2 (0.48) | PTGS1PTGS2MAOBAGPAT2HPGD | |
| SCHEMBL11117595 | 0.73 | PTGS1 (0.47) | PGK1PTGS1PTGS2AGPAT2HPGD | |
| SCHEMBL3805546 | 0.68 | HTT (0.45) | PGK1POLBMAPK1HSD17B10MAOB | |
| SCHEMBL11112461 | 0.68 | PGK1 (0.37) | PGK1POLBMAPK1HSD17B10MAOB | |
| SCHEMBL18475729 | 0.67 | AGPAT2 (0.31) | PGK1AGPAT2 | |
| SCHEMBL19048795 | 0.67 | PGK1 (0.33) | PGK1AGPAT2 | |
| SCHEMBL18791381 | 0.67 | ALDH1A1 (0.36) | HSD17B10HPGDTSHRAKR1B1 | |
| SCHEMBL7074465 | 0.66 | PTGS1 (0.54) | PTGS1PTGS2MAPK1HSD17B10MAOB | |
| SCHEMBL17609927 | 0.65 | ALDH1A1 (0.52) | TSHRAKR1B1LMNA | |
| SCHEMBL11594887 | 0.65 | SMN1; SMN2 (0.42) | POLBHSD17B10HPGDAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044008-B1 | USE OF 2-PROPARGYLOXY-BENZAZOLES AS SYNERGISTS | BAYER AG (DE) | 1984-12-05 | — | — | EP | disclosed |
| EP-0044008-A1 | Use of 2-propargyloxy-benzazoles as synergists | BAYER AG (DE) | 1982-01-20 | — | — | EP | disclosed |