Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113691 | 0.88 | LOXL2 (0.48) | PTGS1PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9852614 | 0.82 | GFER (0.47) | PTGS1PTGS2KMT2ANPC1RAB9A | |
| SCHEMBL11205335 | 0.80 | KMT2A (0.59) | PTGS1PTGS2KMT2ANPC1RAB9A | |
| SCHEMBL20733701 | 0.79 | NPC1 (0.53) | PTGS1PTGS2KMT2ANPC1RAB9A | |
| SCHEMBL7074465 | 0.78 | PTGS1 (0.54) | PTGS1PTGS2KMT2ANPC1RAB9A | |
| SCHEMBL13071505 | 0.74 | NPC1 (0.51) | PTGS1PTGS2KMT2ANPC1RAB9A | |
| SCHEMBL11113555 | 0.73 | PGK1 (0.37) | PTGS1PTGS2LMNAHPGDTSHR | |
| SCHEMBL11117152 | 0.73 | MAOB (0.41) | PTGS1PTGS2RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10568147 | 0.73 | PTGS1 (0.44) | PTGS1PTGS2KMT2ANPC1RAB9A | |
| SCHEMBL19624141 | 0.71 | NPC1 (0.56) | KMT2ANPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044008-B1 | USE OF 2-PROPARGYLOXY-BENZAZOLES AS SYNERGISTS | BAYER AG (DE) | 1984-12-05 | — | — | EP | disclosed |
| EP-0044008-A1 | Use of 2-propargyloxy-benzazoles as synergists | BAYER AG (DE) | 1982-01-20 | — | — | EP | disclosed |