Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102734 | 0.85 | SMN1; SMN2 (0.45) | KCNMA1NPC1POLBRAB9AKLF5 | |
| SCHEMBL11107256 | 0.85 | KCNMA1 (0.46) | KCNMA1NPC1POLBRAB9AKLF5 | |
| SCHEMBL11108597 | 0.85 | ALDH1A1 (0.56) | NPC1POLBRAB9ATDP1ALDH1A1 | |
| SCHEMBL11105633 | 0.83 | ALPL (0.63) | NPC1POLBRAB9AALDH1A1MEN1 | |
| SCHEMBL11556922 | 0.82 | KCNMA1 (0.58) | KCNMA1MEN1KMT2A | |
| SCHEMBL11111705 | 0.82 | RAB9A (0.57) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL11561500 | 0.81 | LRRK2 (0.63) | KMT2A | |
| SCHEMBL10885312 | 0.81 | GCK (0.54) | KCNMA1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL12892213 | 0.80 | MEN1 (0.63) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL11081640 | 0.80 | NPC1 (0.58) | NPC1POLBRAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474792-A | N-Tetrazolyl benzamides and anti-allergic use thereof | RIKER LABORATORIES, INC. (US) | 1984-10-02 | — | — | US | claimed |
| US-4474792-A | N-Tetrazolyl benzamides and anti-allergic use thereof | RIKER LABORATORIES, INC. (US) | 1984-10-02 | — | — | US | disclosed |