SCHEMBL11113589

SCHEMBL11113589

CCOC(=O)CC1Oc2cccc(O)c2-c2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
POLB P06746 2/20 0.42
IDO1 P14902 1/20 0.41
ALDH1A1 P00352 3/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
NR3C1 P04150 2/20 0.38
CES2 O00748 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11105521 0.88 NR3C1 (0.53) CYP1A2NR3C1
SCHEMBL11111357 0.88 POLB (0.43) CYP1A2POLBALDH1A1CA12CA1
SCHEMBL11107694 0.87 L3MBTL1 (0.37) CYP1A2ALDH1A1NR3C1MEN1KMT2A
SCHEMBL11102490 0.86 CYP1A2 (0.51) CYP1A2POLBIDO1ALDH1A1SIGMAR1
SCHEMBL9528244 0.80 CYP1A2 (0.57) CYP1A2POLBIDO1ALDH1A1SIGMAR1
SCHEMBL11111593 0.80 ALDH1A1 (0.56) CYP1A2POLBALDH1A1CA12CA1
SCHEMBL11112200 0.80 CYP1A2 (0.45) CYP1A2POLBIDO1ALDH1A1SIGMAR1
SCHEMBL11113145 0.78 HPGD (0.44) POLBALDH1A1NR3C1KMT2A
SCHEMBL11107214 0.77 ALDH1A1 (0.44) CYP1A2POLBIDO1ALDH1A1MEN1
SCHEMBL11110310 0.77 NR3C1 (0.51) POLBALDH1A1NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4463001-A ANTIULCER AGENTS FARMITALIA CARLO ERBA S.P.A. (IT) 1984-07-31 US disclosed