Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP4 | P49662 | 1/20 | 0.44 |
| ▸ | CASP5 | P51878 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | NCF1 | P14598 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059058 | 0.82 | DYRK1A (0.44) | ADRB1ACHE | |
| SCHEMBL18228033 | 0.82 | ACHE (0.47) | ADRB1ALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL28059059 | 0.81 | MAPK8 (0.47) | ADRB1KDM4EALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL7604060 | 0.80 | ADRB1 (0.64) | ADRB1KDM4EALDH1A1ACHEHRH3 | |
| SCHEMBL4501470 | 0.80 | ADRB1 (0.59) | ADRB1KDM4EALDH1A1ACHEHRH3 | |
| SCHEMBL5797268 | 0.80 | ADRB1 (0.59) | ADRB1KDM4EALDH1A1ACHEHRH3 | |
| SCHEMBL31518606 | 0.80 | ADRB1 (0.59) | ADRB1KDM4EALDH1A1ACHEHRH3 | |
| SCHEMBL5758330 | 0.80 | ADRB1 (0.59) | ADRB1KDM4EALDH1A1ACHEHRH3 | |
| SCHEMBL573580 | 0.80 | ADRB1 (0.59) | ADRB1KDM4EALDH1A1ACHEHRH3 | |
| Hydrochloric Acid SCHEMBL4815955 | 0.79 | ALDH1A1 (0.59) | ADRB1KDM4EALDH1A1ACHEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115714-A1 | Pharmaceutical composition with psychotropic dopaminergic action | SANOFI S.A. (FR) | 1984-08-15 | — | — | EP | disclosed |