Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.45 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.45 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10895136 | 0.87 | TDP1 (0.50) | TDP1GRM8GRM4CYP1A2ALDH1A1 | |
| SCHEMBL9026746 | 0.86 | TDP1 (0.46) | TDP1GRM8GRM4CYP1A2ALDH1A1 | |
| SCHEMBL20623073 | 0.86 | TDP1 (0.46) | TDP1GRM8GRM4CYP1A2ALDH1A1 | |
| SCHEMBL9026753 | 0.84 | GRM8 (0.48) | TDP1GRM8GRM4CYP1A2ALDH1A1 | |
| SCHEMBL6841592 | 0.83 | TDP1 (0.44) | TDP1GRM8GRM4CYP1A2ALDH1A1 | |
| SCHEMBL6841595 | 0.81 | MAPK1 (0.44) | TDP1GRM8GRM4CYP1A2ALDH1A1 | |
| SCHEMBL8643545 | 0.79 | GRM8 (0.47) | TDP1GRM8GRM4CYP1A2ALDH1A1 | |
| SCHEMBL9735630 | 0.78 | PDK1 (0.55) | TDP1GRM8GRM4CYP1A2ALDH1A1 | |
| SCHEMBL11769974 | 0.77 | CYP1A2 (0.58) | TDP1GRM8GRM4CYP1A2ALDH1A1 | |
| SCHEMBL4197252 | 0.77 | CYP1A2 (0.50) | TDP1GRM8GRM4CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107027-A1 | Hair dyeing compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1984-05-02 | — | — | EP | disclosed |