Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113945 | 0.79 | TDP1 (0.47) | GRM8GRM4CYP1A2TDP1ALDH1A1 | |
| SCHEMBL9026753 | 0.76 | GRM8 (0.48) | GRM8GRM4CYP1A2TDP1ALDH1A1 | |
| SCHEMBL9026746 | 0.74 | TDP1 (0.46) | GRM8GRM4CYP1A2TDP1ALDH1A1 | |
| SCHEMBL20623073 | 0.74 | TDP1 (0.46) | GRM8GRM4CYP1A2TDP1ALDH1A1 | |
| SCHEMBL6841595 | 0.73 | MAPK1 (0.44) | GRM8GRM4CYP1A2TDP1ALDH1A1 | |
| SCHEMBL2818967 | 0.72 | GRM8 (0.51) | GRM8GRM4CYP1A2TDP1ALDH1A1 | |
| SCHEMBL10895136 | 0.72 | TDP1 (0.50) | GRM8GRM4CYP1A2TDP1ALDH1A1 | |
| SCHEMBL4197252 | 0.72 | CYP1A2 (0.50) | GRM8GRM4CYP1A2TDP1ALDH1A1 | |
| SCHEMBL6841592 | 0.72 | TDP1 (0.44) | GRM8GRM4CYP1A2TDP1ALDH1A1 | |
| SCHEMBL31248053 | 0.72 | CYP1A2 (0.50) | GRM8GRM4CYP1A2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5851778-A | Analyte assay using a trifunctional conjugate | BECKMAN INSTRUMENTS, INC. (US) | 1998-12-22 | — | — | US | disclosed |
| US-5661019-A | USEFUL IN IMMUNOASSYS AND FOR TARGETED LABELING OF PROTEINS | BECKMAN INSTRUMENTS, INC. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5168057-A | Trifunctional conjugates | BECKMAN INSTRUMENTS, INC. (US) | 1992-12-01 | — | — | US | disclosed |
| WO-1989003041-A2 | TRIDENTATE CONJUGATE AND METHOD OF USE THEREOF | BECKMAN INSTRUMENTS, INC. (US) | 1989-04-06 | — | — | WO | disclosed |
| EP-0310361-A2 | Tridentate conjugate and method of use thereof | BECKMAN INSTRUMENTS, INC. (US) | 1989-04-05 | — | — | EP | disclosed |