Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.67 |
| ▸ | DRD2 | P14416 | 2/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | HTR7 | P34969 | 2/20 | 0.67 |
| ▸ | HTR6 | P50406 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11104845 | 0.91 | ALDH1A1 (0.63) | KDM4ECASP1CASP7SMN1; SMN2MAPT | |
| SCHEMBL11836704 | 0.84 | KDM4E (0.84) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL11633831 | 0.83 | HTR1A (0.85) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL11108098 | 0.82 | LMNA (0.63) | DRD2KDM4ESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11632064 | 0.81 | HTR1A (0.98) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9400933 | 0.80 | HTR1A (0.63) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL11845169 | 0.80 | HTR1A (1.00) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL11835918 | 0.80 | HTR1A (1.00) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL11107178 | 0.79 | HTR1A (0.54) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL11104542 | 0.78 | HTR1A (0.55) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479954-A | ANTIDIABETIC AGENTS | EISAI CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |