Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 6/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4448092 | 0.86 | MAPK14 (0.53) | MAPK13MAPK12MAPK11MAPK14AVPR2 | |
| SCHEMBL14415777 | 0.84 | CES2 (0.50) | MAPK13MAPK12MAPK11MAPK14AVPR2 | |
| SCHEMBL8197244 | 0.83 | RECQL (0.68) | MAPK13MAPK12MAPK11MAPK14RECQL | |
| SCHEMBL9717031 | 0.83 | ABCB1 (0.56) | MAPK13MAPK12MAPK11MAPK14RECQL | |
| SCHEMBL11019993 | 0.82 | RECQL (0.71) | MAPK13MAPK12MAPK11MAPK14RECQL | |
| SCHEMBL8201650 | 0.82 | RECQL (0.49) | MAPK13MAPK12MAPK11MAPK14RECQL | |
| SCHEMBL14528312 | 0.81 | MAPK13 (0.59) | MAPK13MAPK12MAPK11MAPK14RECQL | |
| SCHEMBL11824191 | 0.80 | TP53 (0.57) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL9712425 | 0.79 | KMT2A (0.49) | MAPK13MAPK12MAPK11MAPK14RECQL | |
| SCHEMBL11115683 | 0.79 | RECQL (0.49) | MAPK13MAPK12MAPK11MAPK14RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454350-A | Process for the acylation of halo- or trihalomethylbenzenes | RHONE-POULENC SPECIALITIES CHIMIQUES (FR) | 1984-06-12 | — | — | US | disclosed |
| US-4453012-A | REACTION OF A HALO OR TRIHALOMETHYL BENZENE WITH A TRIHALOMETHYLATED ALIPHATIC OR AROMATIC COMPOUND | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-06-05 | — | — | US | disclosed |