Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712419 | 0.87 | KMT2A (0.52) | ABCB1KMT2AMEN1RAB9ALMNA | |
| SCHEMBL8197244 | 0.86 | RECQL (0.68) | ABCB1KMT2AMEN1LMNARECQL | |
| SCHEMBL8459090 | 0.86 | RAB9A (0.53) | ABCB1KMT2AMEN1RAB9ALMNA | |
| SCHEMBL7208739 | 0.86 | RAB9A (0.59) | KMT2AMEN1RAB9ALMNAKDM4E | |
| SCHEMBL11753699 | 0.85 | TSHR (0.51) | KMT2AMEN1RAB9ALMNAMAPK13 | |
| SCHEMBL144475 | 0.85 | KMT2A (0.70) | ABCB1KMT2AMEN1RAB9ALMNA | |
| SCHEMBL9654244 | 0.85 | RECQL (0.71) | ABCB1KMT2AMEN1RAB9ALMNA | |
| SCHEMBL14528312 | 0.83 | MAPK13 (0.59) | KMT2ALMNARECQLMAPK13MAPK12 | |
| SCHEMBL11109843 | 0.83 | KMT2A (0.52) | ABCB1KMT2AMEN1RAB9ALMNA | |
| SCHEMBL11114080 | 0.83 | MAPK13 (0.55) | KMT2AMEN1LMNARECQLMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499450-A1 | Synthesis of 1-aminoanthraquinone | HOECHST CELANESE CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| US-5130448-A | Condensing ortho substituted benzoic acid and xylene, oxidation, ring closure, ammonolysis and decarboxyalation | HOECHST CELANESE CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |
| US-4277477-A | TREATING CARDIAC ARRHYTHMIA | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-07 | — | — | US | disclosed |
| EP-0000750-A1 | 1,2-Benzisothiazoles and process for their preparation | BASF Aktiengesellschaft (DE) | 1979-02-21 | — | — | EP | disclosed |