Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | GSTA1 | P08263 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115683 | 0.87 | RECQL (0.49) | RECQLBCL2L11BCL2L1MCL1MAOB | |
| SCHEMBL11019993 | 0.83 | RECQL (0.71) | RECQLALDH1A1LMNATP53CES2 | |
| SCHEMBL11843932 | 0.83 | RECQL (0.51) | RECQLGSTA1RAB9AALDH1A1AR | |
| SCHEMBL145258 | 0.83 | RECQL (0.70) | RECQLGSTA1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11114080 | 0.82 | MAPK13 (0.55) | RECQLALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL144475 | 0.80 | KMT2A (0.70) | RECQLGSTA1RAB9AALDH1A1HTT | |
| SCHEMBL145897 | 0.80 | GSTA1 (0.75) | RECQLGSTA1RAB9AALDH1A1HTT | |
| SCHEMBL2924890 | 0.80 | CES2 (0.58) | RECQLGSTA1RAB9ANPC1ALDH1A1 | |
| SCHEMBL9712447 | 0.80 | RECQL (0.45) | RECQLALDH1A1KMT2ATP53CES2 | |
| SCHEMBL11824191 | 0.78 | TP53 (0.57) | RAB9ANPC1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109213-A1 | METHOD FOR PREPARING CHIRAL AMINE COMPOUND | 深圳先进技术研究院 | 2023-06-22 | — | — | WO | disclosed |
| US-RE36832-E | AN ANTICHOLESTEROL AGENT TREATING HYPERCHOLESTEROLEMIA | NIHON NOHYAKU CO., LTD (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0613894-B1 | N-Heteroaryl-N'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO LTD (JP) | 1999-05-06 | — | — | EP | disclosed |
| US-5464863-A | Anticholesterol agents | NIHON NOHYAKU CO., LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0613894-A1 | N-Heteroaryl-N'-phenylurea derivatives, their production and use | NIHON NOHYAKU CO., LTD. (JP) | 1994-09-07 | — | — | EP | disclosed |
| EP-0143688-A1 | Process for the preparation of derivatives of alpha-phenylbenzylidenes of amino-carboxamides starting from the corresponding benzophenones and intermediates | DESHORS (FR) | 1985-06-05 | — | — | EP | disclosed |