Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8179432 | 0.88 | ABCB1 (0.41) | KMT2ARECQLMAPK13MAPK12MAPK11 | |
| SCHEMBL9717031 | 0.82 | ABCB1 (0.56) | KMT2ARECQLMAPK13MAPK12MAPK11 | |
| SCHEMBL8197244 | 0.82 | RECQL (0.68) | KMT2ARECQLMAPK13MAPK12MAPK11 | |
| SCHEMBL8756315 | 0.82 | ALDH1A1 (0.50) | KMT2AALDH1A1CES2CES1MEN1 | |
| SCHEMBL14528312 | 0.79 | MAPK13 (0.59) | KMT2ARECQLMAPK13MAPK12MAPK11 | |
| SCHEMBL9712377 | 0.79 | KMT2A (0.54) | KMT2ARECQLMAPK13MAPK12MAPK11 | |
| SCHEMBL11114080 | 0.79 | MAPK13 (0.55) | KMT2ARECQLMAPK13MAPK12MAPK11 | |
| SCHEMBL1375362 | 0.77 | HDAC8 (0.41) | KMT2AALDH1A1CES2CES1MAPT | |
| SCHEMBL9712554 | 0.77 | CES2 (0.58) | KMT2ARECQLMAPK14ALDH1A1CES2 | |
| SCHEMBL9712419 | 0.76 | KMT2A (0.52) | KMT2ARECQLMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |