Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355959 | 0.90 | SMN1; SMN2 (0.53) | HSD17B1HSD17B2HTTSMN1; SMN2HPGD | |
| SCHEMBL2930577 | 0.87 | HDAC1 (0.54) | SRD5A2MAPK1HSD17B1HSD17B2HTT | |
| SCHEMBL11110423 | 0.87 | SMN1; SMN2 (0.52) | MAPK1HSD17B1HSD17B2HTTSMN1; SMN2 | |
| SCHEMBL7815583 | 0.85 | ATM (0.55) | SRD5A2MAPK1HSD17B1HSD17B2HTT | |
| SCHEMBL11278601 | 0.85 | HTT (0.69) | SRD5A2MAPK1HTTSMN1; SMN2HPGD | |
| SCHEMBL13991056 | 0.85 | CES2 (0.57) | HSD17B1HSD17B2HTTSMN1; SMN2CES2 | |
| SCHEMBL15851085 | 0.81 | HSD17B1 (0.58) | SRD5A2MAPK1HSD17B1HSD17B2HTT | |
| SCHEMBL6234574 | 0.80 | MAPK1 (0.50) | SRD5A2MAPK1HTTSMN1; SMN2HPGD | |
| SCHEMBL9253553 | 0.79 | MAPK1 (0.59) | SRD5A2MAPK1HTTSMN1; SMN2HPGD | |
| SCHEMBL15100942 | 0.79 | SRD5A2 (0.53) | SRD5A2MAPK1HTTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454350-A | Process for the acylation of halo- or trihalomethylbenzenes | RHONE-POULENC SPECIALITIES CHIMIQUES (FR) | 1984-06-12 | — | — | US | disclosed |
| US-4453012-A | REACTION OF A HALO OR TRIHALOMETHYL BENZENE WITH A TRIHALOMETHYLATED ALIPHATIC OR AROMATIC COMPOUND | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-06-05 | — | — | US | disclosed |