Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.50 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.50 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.50 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355959 | 0.90 | SMN1; SMN2 (0.53) | TDP1ALDH1A1SMN1; SMN2CES2CES1 | |
| SCHEMBL7810440 | 0.87 | ACHE (0.52) | ATMTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11110423 | 0.87 | SMN1; SMN2 (0.52) | ATMTDP1ALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL11114087 | 0.85 | SRD5A2 (0.52) | TDP1L3MBTL1ALDH1A1SMN1; SMN2CES2 | |
| SCHEMBL13176760 | 0.85 | HDAC1 (0.56) | ATMTDP1L3MBTL1ALDH1A1ABCC9 | |
| SCHEMBL13991056 | 0.85 | CES2 (0.57) | TDP1ALDH1A1SMN1; SMN2CES2CES1 | |
| SCHEMBL5310854 | 0.83 | ALDH1A1 (0.73) | ATMALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL10007010 | 0.82 | SMN1; SMN2 (0.71) | ATMTDP1L3MBTL1ALDH1A1ABCC9 | |
| SCHEMBL166495 | 0.82 | SMN1; SMN2 (0.71) | ATMTDP1L3MBTL1ALDH1A1ABCC9 | |
| SCHEMBL332679 | 0.82 | ATM (0.61) | ATMTDP1L3MBTL1ALDH1A1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891345-B1 | NOVEL FURAN DIARYLMETHYLIDENE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THERAPEUTICAL USES THEREOF | UNION PHARMA SCIENT APPL (FR) | 2001-08-16 | — | — | EP | disclosed |
| EP-0268112-B1 | A novel aromatic polyether and a process for producing a polyether | ASAHI CHEMICAL IND (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4931530-A | Novel aromatic polyether and a process for producing an ether | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0268112-A2 | A novel aromatic polyether and a process for producing a polyether | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1988-05-25 | — | — | EP | disclosed |