Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 8/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111113 | 0.84 | LMNA (0.59) | P2RX4CES1LMNATSHRMAPK1 | |
| SCHEMBL14305634 | 0.82 | P2RX4 (0.46) | P2RX4CES1LMNATSHRMAPK1 | |
| SCHEMBL11114101 | 0.81 | BCHE (0.50) | P2RX4CES1LMNATSHRMAPK1 | |
| SCHEMBL11622785 | 0.81 | P2RX4 (0.45) | P2RX4CES1LMNATSHRMAPK1 | |
| SCHEMBL4458688 | 0.80 | P2RX4 (0.43) | P2RX4CES1LMNATSHRMAPK1 | |
| SCHEMBL11480627 | 0.77 | GPR84 (0.42) | P2RX4CES1LMNATSHRMAPK1 | |
| SCHEMBL8218074 | 0.77 | P2RX4 (0.41) | P2RX4CES1LMNATSHRMAPK1 | |
| SCHEMBL2211282 | 0.75 | LMNA (0.64) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL12459415 | 0.72 | GPR84 (0.54) | CES1LMNAMAPK1ALDH1A1MEN1 | |
| SCHEMBL31741246 | 0.72 | P2RX4 (0.53) | P2RX4CES1LMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | disclosed |