Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101350 | 0.95 | HTR1A (0.49) | HTR1AKDM4EALDH1A1HPGDHSD17B10 | |
| Maleic Acid SCHEMBL11109374 | 0.92 | HTR1A (0.45) | HTR1AKDM4EALDH1A1HPGDHSD17B10 | |
| Maleic Acid SCHEMBL11110905 | 0.89 | HTR1A (0.44) | HTR1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11106525 | 0.88 | HTR1A (0.53) | HTR1AKDM4EDRD2DRD4 | |
| SCHEMBL11110454 | 0.87 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11106065 | 0.83 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11113868 | 0.82 | KDM4E (0.42) | HTR1AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11102699 | 0.81 | ADRA2A (0.57) | HTR1AKDM4EALDH1A1HPGDDRD2 | |
| Maleic Acid SCHEMBL11114268 | 0.81 | HTR1A (0.47) | HTR1AKDM4EALDH1A1DRD2DRD4 | |
| SCHEMBL11108406 | 0.81 | HTR1A (0.48) | HTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479954-A | ANTIDIABETIC AGENTS | EISAI CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |