Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762963 | 0.84 | CTSB (0.51) | CTSBALDH1A1HCAR2MAPK1L3MBTL1 | |
| SCHEMBL27428409 | 0.80 | CTSB (0.47) | CTSBALDH1A1HCAR2SYKMAPK1 | |
| SCHEMBL9179158 | 0.78 | ALDH1A1 (0.50) | CTSBALDH1A1HCAR2MAPK1L3MBTL1 | |
| SCHEMBL11120017 | 0.76 | CTSB (0.53) | CTSBSYKKMT2ACTSKCTSL | |
| SCHEMBL17903563 | 0.76 | ALDH1A1 (0.50) | CTSBALDH1A1HCAR2SYKMAPK1 | |
| SCHEMBL15249320 | 0.76 | ALDH1A1 (0.50) | CTSBALDH1A1HCAR2SYKMAPK1 | |
| SCHEMBL8393993 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HCAR2MAPK1L3MBTL1SLC6A2 | |
| SCHEMBL8823895 | 0.74 | CTSB (0.50) | CTSBALDH1A1HCAR2MAPK1L3MBTL1 | |
| SCHEMBL15249319 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SYKMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL15250961 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SYKMAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123950-A2 | Intermediates for thymosin alpha 1 and desacetylthymosin alpha 1 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-11-07 | — | — | EP | disclosed |