Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9179158 | 0.85 | ALDH1A1 (0.50) | CTSBALDH1A1HCAR2TDP1MAPK1 | |
| SCHEMBL11114587 | 0.84 | CTSB (0.43) | CTSBALDH1A1HCAR2TDP1MAPK1 | |
| SCHEMBL8393993 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 | |
| SCHEMBL8823895 | 0.80 | CTSB (0.50) | CTSBALDH1A1HCAR2TDP1MAPK1 | |
| SCHEMBL7323732 | 0.78 | ALDH1A1 (0.49) | CTSBALDH1A1HCAR2TDP1MAPK1 | |
| SCHEMBL11115960 | 0.75 | ALDH1A1 (0.43) | CTSBALDH1A1HCAR2TDP1MAPK1 | |
| SCHEMBL9099910 | 0.74 | ALDH1A1 (0.56) | CTSBALDH1A1HCAR2TDP1MAPK1 | |
| SCHEMBL19105358 | 0.74 | CTSB (0.61) | CTSBALDH1A1HCAR2TDP1MAPK1 | |
| SCHEMBL939536 | 0.73 | ALDH1A1 (0.64) | CTSBALDH1A1HCAR2TDP1MAPK1 | |
| SCHEMBL966323 | 0.72 | ALDH1A1 (0.62) | ALDH1A1HCAR2TDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784629-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | Chiroscience Limited (GB) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011209-A1 | PEPTIDYL COMPOUNDS AND THEIR THERAPEUTIC USE AS INHIBITORS OF METALLOPROTEASES | CHIROSCIENCE LIMITED (GB) | 1996-04-18 | — | — | WO | disclosed |