Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42370 | 0.79 | EGFR (0.51) | EGFRAKR1B1MAPTTSHRCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL27729485 | 0.78 | EGFR (0.50) | EGFRAKR1B1MAPTTSHRCYP1A2 | |
| SCHEMBL7589860 | 0.76 | HTR2A (0.53) | EGFRAKR1B1MAPTATMCDC25A | |
| SCHEMBL4664795 | 0.74 | GRM1 (0.49) | EGFRAKR1B1CDC25ATSHRLMNA | |
| SCHEMBL14407922 | 0.74 | HTR2A (0.55) | EGFR | |
| SCHEMBL1389876 | 0.74 | HTR2A (0.55) | EGFRTSHRCYP1A2HTT | |
| SCHEMBL5338882 | 0.74 | LMNA (0.52) | EGFRATMCYP1A2LMNA | |
| Hydrochloric Acid SCHEMBL10743675 | 0.73 | HTR2A (0.53) | EGFRTSHRHTT | |
| SCHEMBL29407826 | 0.72 | S100A4 (0.43) | MAPTTSHRLMNAGAA | |
| SCHEMBL11587148 | 0.72 | EGFR (0.49) | EGFRAKR1B1MAPTATMCDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | disclosed |