Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6010129 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2ATMTACR1HPGDMC4R | |
| SCHEMBL4781784 | 0.82 | ATM (0.47) | SMN1; SMN2ATMTACR1HPGDMC4R | |
| SCHEMBL21077981 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2ATMTACR1HPGDMC4R | |
| SCHEMBL6017363 | 0.80 | SMN1; SMN2 (0.56) | SMN1; SMN2ATMTACR1HPGDMEN1 | |
| SCHEMBL3816356 | 0.79 | MC4R (0.50) | SMN1; SMN2ATMTACR1HPGDMC4R | |
| SCHEMBL5695520 | 0.78 | OPRM1 (0.49) | SMN1; SMN2ATMTACR1HPGDMC4R | |
| SCHEMBL6621636 | 0.77 | ATM (0.49) | SMN1; SMN2ATMTACR1HPGDMC4R | |
| SCHEMBL6026586 | 0.77 | RAB9A (0.51) | SMN1; SMN2ATMTACR1HPGDMEN1 | |
| SCHEMBL16876727 | 0.77 | L3MBTL1 (0.49) | ATMTACR1HPGDMC4RMEN1 | |
| SCHEMBL6859676 | 0.77 | MEN1 (0.47) | ATMTACR1MEN1KMT2AMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |