Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117599 | 0.73 | LMNA (0.43) | SCN4AOPRM1HTR2C | |
| SCHEMBL11119013 | 0.72 | MEN1 (0.38) | SCN4AOPRM1ALDH1A1TSHRMEN1 | |
| SCHEMBL11113548 | 0.72 | SCN4A (0.39) | SCN4AOPRM1CYP3A4HTR2CKCNH2 | |
| SCHEMBL11116061 | 0.71 | SCN4A (0.40) | SCN4AOPRM1HTR2C | |
| SCHEMBL11116317 | 0.70 | SCN4A (0.39) | SCN4AOPRM1 | |
| SCHEMBL11115855 | 0.70 | KDM4E (0.40) | OPRM1ALDH1A1 | |
| SCHEMBL10500113 | 0.70 | SCN4A (0.39) | SCN4AOPRM1 | |
| SCHEMBL11115188 | 0.69 | SCN4A (0.39) | SCN4AOPRM1MEN1KMT2A | |
| SCHEMBL11116215 | 0.69 | SCN4A (0.39) | SCN4AOPRM1HTR2C | |
| SCHEMBL11111207 | 0.69 | SCN4A (0.39) | SCN4AOPRM1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |