Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111810 | 0.74 | SCN4A (0.34) | OPRM1 | |
| SCHEMBL11115924 | 0.72 | OPRM1 (0.33) | OPRM1 | |
| SCHEMBL11114555 | 0.70 | OPRM1 (0.40) | ALDH1A1OPRM1 | |
| SCHEMBL11114801 | 0.70 | SCN4A (0.35) | ALDH1A1OPRM1 | |
| SCHEMBL11117599 | 0.69 | LMNA (0.43) | OPRM1 | |
| SCHEMBL11118656 | 0.69 | OPRM1 (0.37) | OPRM1 | |
| SCHEMBL11114003 | 0.69 | OPRM1 (0.37) | KDM4EALDH1A1OPRM1 | |
| SCHEMBL11119013 | 0.68 | MEN1 (0.38) | ALDH1A1OPRM1 | |
| SCHEMBL11113548 | 0.68 | SCN4A (0.39) | OPRM1 | |
| SCHEMBL11118690 | 0.68 | DPP9 (0.40) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |