Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109993 | 0.87 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2KDM4ELMNA | |
| SCHEMBL11111438 | 0.77 | KDM4E (0.41) | NFE2L2ALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL20113072 | 0.76 | KDM4E (0.42) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL4931404 | 0.75 | LOX (0.41) | ALDH1A1KDM4ELMNAMAPTTDP1 | |
| SCHEMBL11112187 | 0.74 | LMNA (0.40) | NFE2L2ALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL11105601 | 0.73 | NFE2L2 (0.40) | NFE2L2ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL2129407 | 0.72 | SMN1; SMN2 (0.59) | KEAP1NFE2L2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1641021 | 0.72 | MAPT (0.42) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL28125833 | 0.71 | CA1 (0.47) | ALDH1A1HPGDSMN1; SMN2KDM4ELMNA | |
| SCHEMBL28268032 | 0.71 | KDM4E (0.42) | NFE2L2ALDH1A1HPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103660-A1 | Pyridine-1-oxides, herbicidal compositions thereof and herbicidal methods for applying the compounds | UNIROYAL, INC. (US) | 1984-03-28 | — | — | EP | disclosed |