Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954384 | 0.86 | CA2 (0.44) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11109993 | 0.82 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10LMNAHPGD | |
| SCHEMBL11114827 | 0.77 | KEAP1 (0.39) | KDM4ECYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL11105601 | 0.74 | NFE2L2 (0.40) | KDM4EALDH1A1HSD17B10LMNARAB9A | |
| SCHEMBL11112187 | 0.72 | LMNA (0.40) | KDM4ETAAR1ALDH1A1MEN1KMT2A | |
| SCHEMBL20113072 | 0.72 | KDM4E (0.42) | KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL4931404 | 0.71 | LOX (0.41) | KDM4EALDH1A1MAPTLMNA | |
| SCHEMBL11105717 | 0.70 | TAAR1 (0.37) | TAAR1THRATHRBPPARGALDH1A1 | |
| SCHEMBL11110284 | 0.69 | HTT (0.43) | CYP1A2CYP3A4CYP2D6CYP2C19MEN1 | |
| SCHEMBL15461581 | 0.68 | NAPRT (0.42) | KDM4EHSD17B10MAPTNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103660-A1 | Pyridine-1-oxides, herbicidal compositions thereof and herbicidal methods for applying the compounds | UNIROYAL, INC. (US) | 1984-03-28 | — | — | EP | disclosed |