Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 4/20 | 0.48 |
| ▸ | ACACA | Q13085 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113084 | 0.86 | MKNK1 (0.48) | MKNK1MKNK2ACACBACACALMNA | |
| SCHEMBL4709392 | 0.83 | MKNK1 (0.46) | MKNK1MKNK2ACACBACACANPC1 | |
| SCHEMBL29177433 | 0.80 | MKNK1 (0.51) | MKNK1MKNK2NPC1LMNAPKM | |
| SCHEMBL11114300 | 0.79 | CHEK1 (0.48) | MKNK1MKNK2HSD17B1HSD17B2KMT2A | |
| SCHEMBL11116291 | 0.79 | PDGFRB (0.44) | MKNK1MKNK2PKMHSD17B1HSD17B2 | |
| SCHEMBL6027790 | 0.79 | NPC1 (0.50) | MKNK1MKNK2NPC1LMNAPKM | |
| SCHEMBL14974895 | 0.78 | TSHR (0.44) | LMNADGAT1ALDH1A1 | |
| SCHEMBL11114687 | 0.78 | ALDH1A1 (0.47) | OXTRDGAT1ALDH1A1KDM4E | |
| SCHEMBL1422182 | 0.77 | HSD17B1 (0.67) | MKNK1MKNK2NPC1LMNAPKM | |
| SCHEMBL8096967 | 0.76 | ACACB (0.42) | ACACBACACALMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |