Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 6/20 | 0.41 |
| ▸ | ACACA | Q13085 | 4/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459579 | 0.87 | PTK2 (0.50) | MEN1KMT2AALDH1A1MAPTTDP1 | |
| SCHEMBL11114904 | 0.86 | MKNK1 (0.49) | MKNK1MKNK2MEN1KMT2AALDH1A1 | |
| SCHEMBL11116291 | 0.84 | PDGFRB (0.44) | MKNK1MKNK2HSD17B1HSD17B2 | |
| SCHEMBL6224642 | 0.82 | EGLN1 (0.48) | MKNK1MKNK2EGLN1MAP4K4MEN1 | |
| SCHEMBL5052703 | 0.78 | MKNK1 (0.57) | MKNK1MKNK2MEN1KMT2ALTA4H | |
| SCHEMBL13575396 | 0.78 | MKNK1 (0.57) | MKNK1MKNK2MEN1KMT2ALTA4H | |
| SCHEMBL11114300 | 0.78 | CHEK1 (0.48) | MKNK1MKNK2MEN1KMT2AALDH1A1 | |
| SCHEMBL3859187 | 0.77 | LTA4H (0.42) | MKNK1MKNK2EGLN1MAP4K4MEN1 | |
| SCHEMBL28530767 | 0.76 | KMT2A (0.49) | MEN1KMT2A | |
| SCHEMBL8096967 | 0.75 | ACACB (0.42) | MEN1KMT2ALMNAACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |