Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114975 | 0.79 | ALDH1A1 (0.49) | HTR2CNOTUMALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL25638265 | 0.74 | ALDH1A1 (0.49) | HTR2CNOTUMALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL24233699 | 0.72 | KDM4E (0.51) | NOTUMALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL11114519 | 0.72 | HTR4 (0.47) | NOTUMALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL11128528 | 0.72 | EGFR (0.58) | NOTUMALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL9044314 | 0.71 | ALDH1A1 (0.52) | NOTUMALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL12869921 | 0.71 | EGFR (0.60) | NOTUMALDH1A1MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL23147028 | 0.71 | HTT (0.45) | SMN1; SMN2NPC1RAB9AHRH3NPSR1 | |
| SCHEMBL12550927 | 0.70 | ALDH1A1 (0.47) | HTR2CNOTUMALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL1177836 | 0.70 | ALDH1A1 (0.73) | NOTUMALDH1A1MAPK1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |