Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113805 | 0.86 | ALDH1A1 (0.45) | NOTUMKDM4EPDE5AALDH1A1TSHR | |
| SCHEMBL9833890 | 0.81 | PDE5A (0.65) | NOTUMKDM4EPDE5ASRD5A1ALDH1A1 | |
| SCHEMBL9392589 | 0.77 | KDM4E (0.69) | NOTUMKDM4EALDH1A1NPSR1CHRM2 | |
| SCHEMBL19512822 | 0.77 | KDM4E (0.72) | NOTUMKDM4EPDE5AALDH1A1TSHR | |
| SCHEMBL2615249 | 0.74 | MEN1 (0.72) | NOTUMKDM4EPDE5AALDH1A1TSHR | |
| SCHEMBL31182096 | 0.73 | ALDH1A1 (0.62) | KDM4EALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL1744688 | 0.73 | ALDH1A1 (0.62) | KDM4EALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL4572834 | 0.72 | CHRM2 (0.58) | NOTUMKDM4ESRD5A1ALDH1A1NPSR1 | |
| SCHEMBL16471407 | 0.71 | SRD5A1 (0.49) | NOTUMKDM4EPDE5ASRD5A1ALDH1A1 | |
| SCHEMBL15241802 | 0.71 | SRD5A1 (0.49) | NOTUMKDM4EPDE5ASRD5A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | claimed |
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | disclosed |