Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | BAX | Q07812 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041395 | 1.00 | LTA4H (0.52) | LTA4HMTNR1AMTNR1BPPARGPPARA | |
| SCHEMBL17892031 | 0.92 | MTNR1A (0.55) | LTA4HMTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL7566883 | 0.92 | MTNR1A (0.55) | LTA4HMTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL120055 | 0.92 | MTNR1A (0.55) | LTA4HMTNR1AMTNR1BALDH1A1LMNA | |
| SCHEMBL10629728 | 0.85 | MTNR1A (0.44) | LTA4HMTNR1AMTNR1BTSHR | |
| SCHEMBL7976612 | 0.85 | CYP1A2 (0.58) | MTNR1AMTNR1BPPARGPPARAMAPT | |
| SCHEMBL11752459 | 0.85 | CYP1A2 (0.58) | MTNR1AMTNR1BPPARGPPARAMAPT | |
| SCHEMBL7966638 | 0.85 | CYP1A2 (0.58) | MTNR1AMTNR1BPPARGPPARAMAPT | |
| SCHEMBL11283822 | 0.84 | PPARG (0.43) | PPARGPPARAMAOA | |
| SCHEMBL11464422 | 0.83 | SIGMAR1 (0.48) | PPARGPPARAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128648-A1 | Nitrogen-containing heterocyclic compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-19 | — | — | EP | disclosed |