Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 10/20 | 0.47 |
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11752459 | 1.00 | CYP1A2 (0.58) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL7976612 | 1.00 | CYP1A2 (0.58) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL15890439 | 0.92 | PRKAB2 (0.46) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL7566883 | 0.88 | MTNR1A (0.55) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL120055 | 0.88 | MTNR1A (0.55) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL17892031 | 0.88 | MTNR1A (0.55) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL16215835 | 0.87 | PPARA (0.46) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL10629728 | 0.85 | MTNR1A (0.44) | CYP1A2GAACYP2C9PKMCYP2C19 | |
| SCHEMBL4041395 | 0.85 | LTA4H (0.52) | MAPTPPARGPPARAMTNR1AMTNR1B | |
| SCHEMBL11116490 | 0.85 | LTA4H (0.52) | MAPTPPARGPPARAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |
| EP-0971892-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Astra Pharmaceuticals Limited (GB) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042670-A1 | NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-10-01 | — | — | WO | disclosed |