Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117549 | 1.00 | KMT2A (0.43) | KMT2ALMNAGAANPC1SMN1; SMN2 | |
| SCHEMBL5990261 | 0.85 | KMT2A (0.46) | KMT2ALMNAGAANPC1SMN1; SMN2 | |
| SCHEMBL5990255 | 0.85 | KMT2A (0.46) | KMT2ALMNAGAANPC1SMN1; SMN2 | |
| SCHEMBL11117551 | 0.80 | TSHR (0.44) | KMT2ALMNAGAANPC1SMN1; SMN2 | |
| SCHEMBL5990108 | 0.77 | NPC1 (0.53) | KMT2ALMNAGAANPC1SMN1; SMN2 | |
| SCHEMBL10657583 | 0.68 | KMT2A (0.52) | KMT2ALMNAGAANPC1SMN1; SMN2 | |
| SCHEMBL10661540 | 0.68 | NPC1 (0.46) | KMT2ALMNAGAANPC1SMN1; SMN2 | |
| SCHEMBL10657588 | 0.68 | KMT2A (0.52) | KMT2ALMNAGAANPC1SMN1; SMN2 | |
| SCHEMBL7531772 | 0.68 | GRIK1 (0.52) | KMT2ALMNAGAANPC1SMN1; SMN2 | |
| SCHEMBL10713056 | 0.67 | RORC (0.56) | KMT2ALMNAALDH1A1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434100-A | TRANQUILIZING, ANTICONVULSANTS, ANXIOLYTIC | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| US-4356176-A | TRANQUILIZERS, ANTICONVULSANT | CIBA-GEIGY CORPORATION (US) | 1982-10-26 | — | — | US | disclosed |
| US-4315926-A | ANXIOLYTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |