Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.56 |
| ▸ | RORB | Q92753 | 3/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306685 | 0.91 | LMNA (0.63) | KCNMA1LMNAPOLBTSHRALDH1A1 | |
| SCHEMBL13798207 | 0.90 | RECQL (0.62) | KCNMA1KDM4EHIF1ALMNAPOLB | |
| SCHEMBL8785645 | 0.89 | KCNMA1 (0.63) | RORCRORBKCNMA1KDM4EHIF1A | |
| SCHEMBL2705425 | 0.89 | RECQL (0.65) | RORCRORBKCNMA1KDM4EHIF1A | |
| SCHEMBL5990108 | 0.88 | NPC1 (0.53) | KCNMA1KDM4EHIF1ALMNAPOLB | |
| SCHEMBL31186154 | 0.87 | MAPK13 (0.60) | RORCRORBKCNMA1KDM4EHIF1A | |
| SCHEMBL6103175 | 0.85 | POLB (0.66) | KDM4ELMNAPOLBTSHRALDH1A1 | |
| SCHEMBL28098625 | 0.85 | LMNA (0.54) | KCNMA1LMNAPOLBTSHRALDH1A1 | |
| SCHEMBL322168 | 0.84 | CTSD (0.62) | LMNA | |
| SCHEMBL29658169 | 0.84 | CTSD (0.62) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661595-A | TREATING KETONE COMPOUND WITH S OR SULFIDE | SANDOZ LTD. (CH) | 1987-04-28 | — | — | US | disclosed |