Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756707 | 0.79 | HDAC4 (0.34) | ATMMAOBMAOAMEN1KMT2A | |
| SCHEMBL7294434 | 0.72 | ATM (0.33) | ATMMEN1KMT2AHTR2AHRH1 | |
| SCHEMBL7439980 | 0.70 | HTR2C (0.50) | MAOBMAOABCHEADRA2BADRA2C | |
| SCHEMBL6034027 | 0.68 | MAPT (0.43) | MEN1KMT2AMAPTHDAC4HDAC7 | |
| SCHEMBL4515519 | 0.68 | IDO1 (0.33) | MAPTHDAC4HDAC7HDAC5ALDH1A1 | |
| SCHEMBL4515525 | 0.68 | ALDH1A1 (0.33) | MEN1KMT2AMAPTHTR2AHRH1 | |
| SCHEMBL2580148 | 0.67 | MAOA (0.53) | MAOBMAOAMAPTMTNR1AMTNR1B | |
| SCHEMBL31276808 | 0.66 | HTR2A (0.35) | MAOBMAOAMAPTHTR2AHRH1 | |
| SCHEMBL2525691 | 0.66 | HTR2A (0.35) | ATMMAOBMAOAMAPTHTR2A | |
| SCHEMBL4440305 | 0.66 | HTR2A (0.35) | MAOBMAOAMAPTHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122155-A2 | Improvements in or relating to naphthylglycyl cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |