Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515525 | 0.83 | ALDH1A1 (0.33) | IDO1ALDH1A1MAPTHDAC4HDAC7 | |
| SCHEMBL7756707 | 0.71 | HDAC4 (0.34) | ALDH1A1MAPTHDAC4HDAC7HDAC5 | |
| SCHEMBL4504652 | 0.69 | HDAC4 (0.35) | ALDH1A1MAPTHDAC4HDAC7HDAC5 | |
| SCHEMBL4440305 | 0.69 | HTR2A (0.35) | ALDH1A1MAPTHDAC4HDAC7HDAC5 | |
| SCHEMBL31276808 | 0.69 | HTR2A (0.35) | ALDH1A1MAPTHDAC4HDAC7HDAC5 | |
| SCHEMBL11117723 | 0.68 | ATM (0.36) | ALDH1A1MAPTHDAC4HDAC7HDAC5 | |
| SCHEMBL22139620 | 0.66 | — | — | |
| SCHEMBL4512600 | 0.66 | ALDH1A1 (0.60) | ALDH1A1 | |
| SCHEMBL8849849 | 0.65 | HTR2A (0.36) | ALDH1A1MAPT | |
| SCHEMBL2525691 | 0.65 | HTR2A (0.35) | ALDH1A1MAPTHDAC4HDAC7HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233960-A1 | Kinase Inhibitors | DEVGEN NV (BE) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233960-A1 | Kinase Inhibitors | ROCK1, MAP3K1, MAP3K11 | IDO1 2653/4885ALDH1A1 2810/4885MAPT 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.