Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117862 | 1.00 | GPR3 (0.41) | GPR3ARSMN1; SMN2NTSR1MAPK1 | |
| SCHEMBL11111670 | 0.92 | HDAC8 (0.40) | GPR3ARNTSR1MAPK1ALDH1A1 | |
| SCHEMBL11111667 | 0.92 | HDAC8 (0.40) | GPR3ARNTSR1MAPK1ALDH1A1 | |
| SCHEMBL677773 | 0.82 | MEN1 (0.42) | ALDH1A1LMNACYP1A2CYP2D6HPGD | |
| SCHEMBL29454416 | 0.82 | MEN1 (0.42) | ALDH1A1LMNACYP1A2CYP2D6HPGD | |
| SCHEMBL1233660 | 0.79 | MEN1 (0.49) | SMN1; SMN2ALDH1A1CYP1A2CYP2D6HPGD | |
| SCHEMBL11115316 | 0.78 | HSD17B3 (0.38) | GPR3ARSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL11115938 | 0.78 | HSD17B3 (0.38) | GPR3ARSMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL9205791 | 0.74 | GPR3 (0.45) | GPR3SMN1; SMN2ALDH1A1LMNACYP1A2 | |
| SCHEMBL11118131 | 0.72 | S100A4 (0.38) | ARALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | disclosed |