Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115938 | 1.00 | HSD17B3 (0.38) | HSD17B3S100A4GPR3ARPDPK1 | |
| SCHEMBL11118131 | 0.91 | S100A4 (0.38) | HSD17B3S100A4ARPDPK1ALDH1A1 | |
| SCHEMBL11115877 | 0.91 | S100A4 (0.38) | HSD17B3S100A4ARPDPK1ALDH1A1 | |
| SCHEMBL11115874 | 0.91 | S100A4 (0.38) | HSD17B3S100A4ARPDPK1ALDH1A1 | |
| SCHEMBL29454416 | 0.85 | MEN1 (0.42) | ALDH1A1TP53MEN1LMNAMAPT | |
| SCHEMBL677773 | 0.85 | MEN1 (0.42) | ALDH1A1TP53MEN1LMNAMAPT | |
| SCHEMBL11117862 | 0.78 | GPR3 (0.41) | GPR3ARALDH1A1HTTLMNA | |
| SCHEMBL11117865 | 0.78 | GPR3 (0.41) | GPR3ARALDH1A1HTTLMNA | |
| SCHEMBL11116115 | 0.78 | TRPA1 (0.40) | ALDH1A1TP53NPSR1MEN1LMNA | |
| SCHEMBL11111901 | 0.78 | TRPA1 (0.40) | ALDH1A1TP53NPSR1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | claimed |
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | disclosed |