Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2218979 | 0.88 | KMT2A (0.44) | POLBCTDSP1KMT2AALDH1A1MAOB | |
| SCHEMBL11123940 | 0.85 | OPRK1 (0.49) | POLBCTDSP1KMT2AALDH1A1MAOB | |
| SCHEMBL11121410 | 0.84 | RXRA (0.46) | POLBCTDSP1KMT2AALDH1A1MAOB | |
| SCHEMBL13994548 | 0.83 | KMT2A (0.50) | POLBCTDSP1KMT2AALDH1A1MAOB | |
| SCHEMBL11119281 | 0.80 | ALDH1A1 (0.57) | POLBALDH1A1MAOBMAPTL3MBTL1 | |
| SCHEMBL2218387 | 0.80 | KMT2A (0.39) | POLBCTDSP1KMT2AALDH1A1MAOB | |
| SCHEMBL2218889 | 0.79 | KMT2A (0.41) | POLBCTDSP1KMT2AALDH1A1MAOB | |
| SCHEMBL2218188 | 0.77 | KMT2A (0.40) | POLBCTDSP1KMT2AALDH1A1MAOB | |
| SCHEMBL1887763 | 0.74 | KMT2A (0.44) | POLBCTDSP1KMT2AALDH1A1KDM4E | |
| SCHEMBL12419178 | 0.73 | KDM4E (0.47) | POLBCTDSP1KMT2AALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461835-A | RESOLVING ARYLOXY-A-ALKYL ESTERS TO MAKE VITAMIN E INTERMEDIATES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1984-07-24 | — | — | US | disclosed |