SCHEMBL111190

SCHEMBL111190

Nc1ccc(NCCO)cc1[N+](=O)[O-]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.50
ALDH1A1 P00352 6/20 0.50
KMT2A Q03164 5/20 0.50
TDP1 Q9NUW8 4/20 0.50
MEN1 O00255 4/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
ALOX15 P16050 1/20 0.50
FFAR4 Q5NUL3 1/20 0.49
GAA P10253 2/20 0.48
HTT P42858 2/20 0.48
HPGD P15428 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TSHR P16473 2/20 0.48
LMNA P02545 1/20 0.47
RAB9A P51151 1/20 0.47
HTR6 P50406 1/20 0.45
ADRB2 P07550 1/20 0.45
PKM P14618 1/20 0.43
GLA P06280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6001711 0.88 ALDH1A1 (0.67) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL8723933 0.88 TSHR (0.50) MAPTALDH1A1TDP1POLBGAA
SCHEMBL11772638 0.86 KMT2A (0.49) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL2470791 0.86 HTR6 (0.59) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL6151067 0.84 MAPT (0.50) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL127370 0.83 ALDH1A1 (0.68) MAPTALDH1A1KMT2ATDP1POLB
SCHEMBL29392416 0.83 ALDH1A1 (0.68) MAPTALDH1A1KMT2ATDP1POLB
SCHEMBL3378074 0.83 EGFR (0.61) MAPTALDH1A1KMT2ATDP1POLB
SCHEMBL17767775 0.82 LMNA (0.50) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL2938667 0.81 MEN1 (0.54) MAPTALDH1A1KMT2ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1974 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112029310-B Special new material rubber shock pad and preparation method thereof 广州宝来声学材料有限公司 2022-04-01 CN claimed
WO-2021121823-A1 TINTING CONDITIONER HAVING IMPROVED DYEING PERFORMANCE HENKEL AG & CO. KGAA (DE) 2021-06-24 WO claimed
CN-112029310-A Special new material rubber shock pad and preparation method thereof 广州宝来声学材料有限公司 2020-12-04 CN claimed
EP-1437123-B2 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME L'ORÉAL (FR) 2017-11-08 EP claimed
EP-3034067-A1 Hair colouring compositions Unilever PLC (GB) 2016-06-22 EP claimed
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 EP claimed
EP-0999823-B2 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME OREAL (FR) 2011-10-05 EP claimed
US-7799092-B2 Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer L'OREAL S.A. (FR) 2010-09-21 US claimed
US-7736395-B2 direct dyes L'OREAL S.A. (FR) 2010-06-15 US claimed
EP-1738801-B1 Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid OREAL (FR) 2010-06-09 EP claimed
WO-1988004166-A1 HAIR DYEING OXIDISING AGENT AND PROCESS WITH 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES AND NEW 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES WELLA AKTIENGESELLSCHAFT (DE) 1988-06-16 WO claimed
US-4725282-A LOW VISCOSITY; STORAGE STABILITY WELLA AKTIENGESELLSCHAFT (DE) 1988-02-16 US claimed
EP-0166155-B1 2-ALKYLSULPHONYL-1,4-DIAMINOBENZENES, PROCESS FOR THEIR PREPARATION AND OXIDATIVE HAIR-DYEING COMPOSITIONS CONTAINING THESE COMPOUNDS Wella Aktiengesellschaft (DE) 1987-09-23 EP claimed
EP-0226072-A1 Oxidation dye containing 4-amino-2-aminomethyl phenol Wella Aktiengesellschaft (DE) 1987-06-24 EP claimed
WO-1987003475-A2 OXIDIZING HAIR DYER BASED ON 4-AMINO-2-AMINOMETHYLPHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1987-06-18 WO claimed
EP-0203446-A1 Nitro-p-phenylene diamine derivatives, process for their preparation and hair dye compositions containing these compounds Wella Aktiengesellschaft (DE) 1986-12-03 EP claimed
CN-85103112-A Oxide hair dye based on the low viscosity carrier material 1986-10-22 CN claimed
WO-1986000303-A1 TWO-ALKYL-SULPHONYL-1,4-DIAMINOBENZENES, PREPARATION THEREOF AND UTILISATION THEREOF WELLA AKTIENGESELLSCHAFT (DE) 1986-01-16 WO claimed
EP-0166155-A1 2-Alkylsulphonyl-1,4-diaminobenzenes, process for their preparation and oxidative hair-dyeing compositions containing these compounds Wella Aktiengesellschaft (DE) 1986-01-02 EP claimed
US-4543425-A 1,3-Diamino-4-(2',2',2',-trifluoroethoxy)-benzene, method of producing the same, and hair coloring composition containing the same WELLA AG (DE) 1985-09-24 US claimed