Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 10/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111190 | 0.88 | MAPT (0.50) | TSHRTDP1ALDH1A1MAPTGLA | |
| SCHEMBL6440712 | 0.86 | MAPT (0.60) | TSHRTDP1ALDH1A1MAPTGLA | |
| SCHEMBL14979009 | 0.83 | KAT2B (0.55) | TSHRTDP1ALDH1A1MAPTGLA | |
| SCHEMBL2467753 | 0.83 | ALDH1A1 (0.56) | TSHRTDP1ALDH1A1MAPTGLA | |
| SCHEMBL2467881 | 0.83 | GPR35 (0.50) | TSHRTDP1ALDH1A1MAPTGLA | |
| SCHEMBL29353354 | 0.82 | TDP1 (0.47) | TSHRTDP1ALDH1A1MAPTGLA | |
| SCHEMBL28673730 | 0.82 | TDP1 (0.47) | TSHRTDP1ALDH1A1MAPTGLA | |
| SCHEMBL14266750 | 0.81 | ALDH1A1 (0.55) | TSHRTDP1ALDH1A1MAPTGLA | |
| SCHEMBL15221111 | 0.81 | MAPT (0.54) | TSHRTDP1ALDH1A1MAPTGLA | |
| SCHEMBL12289538 | 0.81 | MAPT (0.66) | TSHRTDP1ALDH1A1MAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863739-A2 | HAIR DYE | Wella Aktiengesellschaft (DE) | 1998-09-16 | — | — | EP | disclosed |
| WO-1998011863-A2 | HAIR DYE | WELLA AKTIENGESELLSCHAFT (DE) | 1998-03-26 | — | — | WO | disclosed |