Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849662 | 0.91 | CNR2 (0.48) | AOC3MEN1KMT2AGAAADRB2 | |
| SCHEMBL30849673 | 0.90 | PPARG (0.51) | MEN1KMT2AADRB2CYP3A4PPARG | |
| SCHEMBL30849665 | 0.90 | PPARG (0.50) | AOC3MEN1KMT2AGAAPPARG | |
| SCHEMBL3070798 | 0.90 | PPARG (0.50) | AOC3MEN1KMT2AGAAPPARG | |
| SCHEMBL19922926 | 0.87 | ALOX15 (0.53) | MEN1KMT2AGAAALOX15TSHR | |
| SCHEMBL28308319 | 0.87 | AOC3 (0.41) | AOC3TAAR1MEN1KMT2AGAA | |
| SCHEMBL9460441 | 0.83 | MEN1 (0.49) | AOC3TAAR1MEN1KMT2AGAA | |
| SCHEMBL14839523 | 0.83 | ADRB2 (0.51) | MEN1KMT2AADRB2PPARGPPARA | |
| SCHEMBL2964767 | 0.81 | ADRB2 (0.62) | TAAR1ADRB2ALOX15TSHRNFKB1 | |
| SCHEMBL8113426 | 0.80 | AOC3 (0.52) | AOC3GAATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028305-B1 | DIARYL COMPOUNDS AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-02-01 | — | — | EP | disclosed |
| EP-0028305-A1 | Diaryl compounds and pharmaceutical formulations containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1981-05-13 | — | — | EP | disclosed |