Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849665 | 0.93 | PPARG (0.50) | PPARGPPARAMEN1KMT2AHTR1A | |
| SCHEMBL3070798 | 0.93 | PPARG (0.50) | PPARGPPARAMEN1KMT2AHTR1A | |
| SCHEMBL11119802 | 0.90 | AOC3 (0.47) | PPARGPPARAMEN1KMT2ACNR2 | |
| SCHEMBL936320 | 0.90 | PPARG (0.58) | PPARGPPARAMEN1KMT2ACYP2D6 | |
| SCHEMBL499868 | 0.86 | PPARG (0.54) | PPARGPPARACYP2D6CYP2C19RIPK1 | |
| SCHEMBL5835025 | 0.86 | PPARG (0.54) | PPARGPPARACYP2D6CYP2C19RIPK1 | |
| SCHEMBL477470 | 0.86 | PPARG (0.54) | PPARGPPARACYP2D6CYP2C19RIPK1 | |
| SCHEMBL14839521 | 0.84 | PPARG (0.54) | PPARGPPARAMEN1KMT2AHTR1A | |
| SCHEMBL19152252 | 0.83 | MMP12 (0.57) | PPARGPPARARIPK1LMNAADRB2 | |
| SCHEMBL1837304 | 0.83 | MEN1 (0.54) | PPARGPPARAMEN1KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865776-A | Method for directly converting aromatic alkyne into chiral alcohol by one-pot method | 三峡大学 | 2024-04-12 | — | — | CN | disclosed |