Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849665 | 1.00 | PPARG (0.50) | PPARGPPARAKMT2AMEN1SLC6A2 | |
| SCHEMBL30849673 | 0.93 | PPARG (0.51) | PPARGPPARAKMT2AMEN1SLC6A2 | |
| SCHEMBL11119802 | 0.90 | AOC3 (0.47) | PPARGPPARAKMT2AMEN1CNR2 | |
| SCHEMBL936318 | 0.90 | PPARG (0.50) | PPARGPPARASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL499868 | 0.86 | PPARG (0.54) | PPARGPPARASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5835025 | 0.86 | PPARG (0.54) | PPARGPPARASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL477470 | 0.86 | PPARG (0.54) | PPARGPPARASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13232175 | 0.85 | RAB9A (0.50) | PPARGPPARAKMT2AMEN1SLC6A2 | |
| SCHEMBL30849683 | 0.85 | RAB9A (0.50) | PPARGPPARAKMT2AMEN1SLC6A2 | |
| SCHEMBL29861111 | 0.85 | MMP12 (0.50) | PPARGPPARASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112262139-B | Aminopyrrolotriazines as kinase inhibitors | 百时美施贵宝公司 | 2023-07-25 | — | — | CN | disclosed |
| US-7795166-B2 | Functional group-selective hydrogenation catalyst and functional group-selective hydrogenation method | N.E. CHEMCAT CORPORATION (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20070155617-A1 | FUNCTIONAL GROUP-SELECTIVE HYDROGENATION CATALYST AND FUNCTIONAL GROUP-SELECTIVE HYDROGENATION METHOD | N. E. CHEMCAT CORPORATION (JP) | 2007-07-05 | — | — | US | disclosed |