Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1754891 | 0.80 | CYP2C19 (0.35) | TSHRSMN1; SMN2KDM4EMAPTCYP3A4 | |
| SCHEMBL194133 | 0.77 | KDM4E (0.40) | TSHRKDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL16308021 | 0.77 | KDM4E (0.40) | TSHRKDM4EMAPTCYP3A4ALOX15 | |
| SCHEMBL3802806 | 0.76 | CYP2C19 (0.36) | TSHRSMN1; SMN2KDM4EMAPTCYP3A4 | |
| SCHEMBL2488648 | 0.76 | CYP2C19 (0.36) | TSHRSMN1; SMN2KDM4EMAPTCYP3A4 | |
| SCHEMBL252297 | 0.76 | CYP3A4 (0.37) | TSHRSMN1; SMN2KDM4EMAPTCYP3A4 | |
| SCHEMBL19914871 | 0.76 | TRPA1 (0.38) | TSHRTRPA1SMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL10792318 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL2950286 | 0.74 | CYP2C19 (0.35) | TSHRSMN1; SMN2KDM4EMAPTCYP3A4 | |
| SCHEMBL17616783 | 0.72 | CYP2C19 (0.34) | TSHRSMN1; SMN2KDM4EMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220447-B | Silicon compound and its manufacture method and its application | 东洋橡胶工业株式会社 | 2017-09-01 | — | — | CN | disclosed |
| CN-104220447-A | Silicon compound and method for producing same, and use thereof | TOYO TIRE & RUBBER CO | 2014-12-17 | — | — | CN | disclosed |
| US-4430326-A | Method of diminishing glucose levels resulting from endogenous glucagon | UNIVERSITY PATENTS, INC. (US) | 1984-02-07 | — | — | US | disclosed |