Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HRH1 | P35367 | 4/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119745 | 0.93 | ALDH1A1 (0.39) | TBXAS1MAPK14SLC6A2SLC6A4HTR2B | |
| SCHEMBL11117688 | 0.88 | HTR2B (0.44) | TBXAS1MAPK14SLC6A2SLC6A4HTR2B | |
| SCHEMBL11114115 | 0.87 | TBXAS1 (0.39) | TBXAS1SLC6A2HTR2BHTR2CHTR2A | |
| SCHEMBL11112746 | 0.87 | TBXAS1 (0.43) | TBXAS1SLC6A2SLC6A4HTR2BHTR2C | |
| SCHEMBL11117014 | 0.86 | TBXAS1 (0.38) | TBXAS1SLC6A2SLC6A4HTR2BHTR2C | |
| SCHEMBL11113224 | 0.86 | TBXAS1 (0.40) | TBXAS1HTR2CHTR2AHRH1ALDH1A1 | |
| SCHEMBL11113630 | 0.85 | HTR2B (0.41) | TBXAS1HTR2BHTR2CHTR2AHRH1 | |
| SCHEMBL11110382 | 0.84 | SMPD1 (0.42) | TBXAS1HTR2BHTR2CHTR2ADRD2 | |
| SCHEMBL11115157 | 0.84 | HTR2B (0.43) | TBXAS1SLC6A2SLC6A4HTR2BHTR2C | |
| SCHEMBL11111272 | 0.83 | TBXAS1 (0.36) | TBXAS1HTR2CHTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038564-B1 | DIBENZ (B,E) OXEPIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1984-09-12 | — | — | EP | disclosed |
| US-4396550-A | ANTICHOLINERGIC, ANTIHISTIMINIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-08-02 | — | — | US | disclosed |